Hospital and clinical pharmacy mcqs (31-40)
31.After oral administration, drugs will generally be absorbed best from the
A. Buccal cavity
B. Stomach
C. Duodenum
D. Ileum
Ans. C
32.The passage of drug molecules across a cell membrane from a region of high drug concentration is known as
A. Active transport
B. Bio availability
C. Biotransformation
D. Passive diffusion
Ans. D
33.Creatinine clearance is used as measurement of
A. Renal excetion rate
B. Glimerular filtration rate (GFR)
C. Active renal secretion
D. Passive renal absorption
Ans. B
34.How long after the dose would exactly 75% of the drug be eliminated from the patient
A. 2 hours
B. 4 hours
C. 6 hours
D. 8 hours
Ans. A
35.The equation that describes the rate of drug dissolution from a tablet is known as
A. Noyes whitney equation
B. Fick's law
C. Law of mass action
D. Henderson-Hassel balch equation
Ans. A
36.Dose dumping is a problem in the formulation of
A. Compressed tablets
B. Hard gelatin capsules
C. Soft gelatin capsules
D. Modified release drug products
Ans. D
37.The intensity of the pharmacological action of a drug is most dependent upon the
A. Concentration of the drug at the receptor site
B. Elimination half-life of the drug
C. Onset time of the drug after oral administration
D. Minimum toxic drug concentration in the plasma
Ans. A
38.The renal clearance of inulin is used as a measurement of
A. Effective renal blood flow
B. Rate of renal drug excretion
C. Glomerular filtration rate
D. Active renal secretion
Ans. C
39.Antacid preparations may stain the stool
A. Red
B.white
C.Orange
D.purple
Ans.B
40.Lidocaine HCl is not administered orally because it is
A.Ineffective by this route
B.Too acidic
C.Too toxic by this route
D.Unstable
Ans.A
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